Cat. No.
MABL-014
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
n/a
Clone No.
GNC92H2
From
Recombinant Antibody
Specificity
Specifically binds to Benzoylmethylecgonine (Cocaine) with a Kd= 4E-7, which is 100-fold difference in Kd to the carboxylic acid metabolite Benzoylmethylecgonine
Alternative Names
Benzoylmethylecgonine
UniProt
Immunogen
Benzoylecgonine-KLH conjugate.
Application Notes
This antibody binds to cocaine, a strong stimulant used clinically as a local analgesic and vasoconstrictor, as well as illegally as a recreational drug.
Antibody First Published
Larsen et al. 2001 Crystal Structure of a Cocaine-binding Antibody. Journal of Molecular Biology 2001; 311:9-15 PMID:11469854
Note on publication
Describes the generation and humanisation of a cocaine-binding antibody and the determination of its crystal structure.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
