Cat. No.
MABL-073
Application
IB, IP, IF
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
K39/25
From
Recombinant Antibody
Specificity
This antibody is specific for the ectodomain of the Kv2.1 potassium channel.
Alternative Names
K39/25R; potassium voltage-gated channel subfamily B member 1; voltage-gated potassium channel subunit Kv2.1; DRK1; h-DRK1; KCNB1; Q03717; P15387
UniProt
Q14721
Immunogen
This antibody was raised by immunising BALB/c mice with a synthetic peptide corresponding to the extracellular S1-S2 loop (amino acids 211-229) of human Kv2.1
Application Notes
This antibody has been used in immunoblot analysis of adult rat brain membranes (Andrews et al, 2019; PMID:30667360), as well as in immunofluorescence analysis of surface Kv2.1 expression by rat hippocampal neurons transfected with Kv2.1 (Lim et al, 2000). This antibody has also been used in immunoprecipitation analysis of mouse brain samples (Pelota et al, 2011).
Antibody First Published
Lim et al. A Novel Targeting Signal for Proximal Clustering of the Kv2.1 K+ Channel in Hippocampal Neurons Neuron. 2000;25(2): 385‐397. PMID:10719893
Note on publication
Describes the original generation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
