Cat. No.
MABL-084
Application
IB, IP
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
L42/17
From
Recombinant Antibody
Specificity
This antibody is specific for SynDIG1.
Alternative Names
L42/17R; Synapse differentiation-inducing gene protein 1; Dispanin subfamily C member 2; Transmembrane protein 90B; DSPC2; Tmem90b; C20orf39
UniProt
A2ANU3
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein corresponding to the cytoplasmic N-terminus (amino acids 1-183) of mouse SynDIG.
Application Notes
The specificity of this antibody has been confirmed in immunoblot analysis of extracts from HEK293 and COS cells transfected with HA-SynDIG1, where this antibody recognises a single band (Kalashnikova et al, 2010), This antibody has been used in immunoblot analysis of membranes prepared from adult rat (Andrews et al, 2019; PMID:30667360) and mouse brain (Kalashnikova et al, 2010).Additionally, this antibody has been used to immunoprecipitate P14 mouse brain extracts (Kalashnikova et al, 2010).
Antibody First Published
Kalashnikova et al. SynDIG1: An Activity-Regulated, AMPA- Receptor- Interacting Transmembrane Protein that Regulates Excitatory Synapse Development Neuron. 2010 Jan 14;65(1):80-93. PMID:20152115
Note on publication
Describes the original generation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
