Cat. No.
MABL-090
Application
WB, IF, IHC
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
N110/29.4
From
Recombinant Antibody
Specificity
This antibody is specific for the neuroligin-3 antigen. Cell surface protein involved in cell-cell- interactions via its interactions with neurexin family members.
Alternative Names
N110/29.4R; Gliotactin homolog; N110/29; S110-29
UniProt
Q62889
Immunogen
This antibody was raised by immunising BALB/c mice with the neuroligin-G antigen.
Application Notes
The antibody was used in immunofluorescense in research on synapses (Davenport et al, 2019; PMID:30784587). This antibody was used for immunohistochemistry in research on the retromer which is an endosomal trafficking complex (Binda et al, 2019; PMID:30602588). Western blotting is a technique usable with this antibody in research on retromers (Binda et al, 2019; PMID:30602588).
Antibody First Published
Binda et al Sorting nexin 27 rescues neuroligin 2 from lysosomal degradation to control inhibitory synapse number. Biochem J. 2019 Jan 25;476(2):293-306. PMID:30602588
Note on publication
Describes research of the retromer which is an evolutionarily conserved endosomal trafficking complex that mediates the retrieval of cargo proteins from a degradative pathway for sorting back to the cell surface.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
