Anti-Thy1.1 mAbs

Cat. No.

MABL-001

Name

Anti-Thy1.1 mAbs

Clone No.

AFD-OX7

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, IHC

Species Reactivity

Rat, Mouse

Basic Information

Specificity

Rat CD90, also known as Thy1.1, a   GPI-anchored membrane protein containing a single V type Ig-like domain.

Alternative Name

CD90; Thy-1 antigen; OX-7 UniProt   Accession Number of Target Protein

UniProt

P01830

Immunogen

Rat Thy- 1L+ antigen in complete   Freund's adjuvant.

Application Notes

This antibody binds to Thy1.1, which   is allelically restricted between different host strains. Administration of   OX7 leads to anti-Thy1 Glomerulonephritis.

Antibody First Published

Mason DW, Williams AF. The kinetics   of antibody binding to membrane antigens in solution and at the cell surface.   Biochem J. 1980 Apr 1;187(1):1-20. PMID:6967725

Note on publication

Describes the generation of the   antibody, shows it recognised Thy1.1 (Thy-1) by immuno-blotting of cell lines   including thymocytes, neuronal cells, stem cells, immature B cells and   connective tissues.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.