Anti-Neural/glial antigen 2 (NG2) mAbs

Cat. No.

MABL-002

Name

Anti-Neural/glial antigen 2 (NG2)   mAbs

Clone No.

AFD-9.2.27

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, FC, IF

Species Reactivity

Human

Basic Information

Specificity

This antibody is specific for human   neural/glial antigen 2.

Alternative Name

CSPG4; melanoma chondroitin sulfate   proteoglycan; MCSP; CSP

UniProt

Q6UVK1

Immunogen

The original antibody was generated   by immunizing Balb/c mice with a 4M urea extract derived from human melanoma   cells (M14).

Application Notes

This antibody binds to   melanoma-associated chondroitin sulphate proteoglycan, which stabilises   cell-substratum interactions during the early stages of melanoma spreading.

Antibody First Published

Morgan et al. Production and   characterization of monoclonal antibody to a melanoma specific glycoprotein.   Hybridoma. 1981;1(1):27-36. PMID:6208119

Note on publication

The original publication details the   production and characterization of a monoclonal antibody which recognizes a   240K dalton glycoprotein specific to melanoma cells.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.