Key features and details | |
Cat. No. | MABL-021 |
Name | Anti-ROBO-1 mAbs |
Clone No. | AFD-B2212A |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody binds specifically to the fn3-fibronectin domain of Human ROBO-1. |
Alternative Name | Roundabout-1 |
UniProt | Q9Y6N7 |
Immunogen | Human recombinant ROBO-1. |
Application Notes | This antibody binds to human ROBO-1, a receptor for SLIT1 and SLIT2. ROBO-1 is involved in axonal navigation, lung development, and cell migration. |
Antibody First Published | Ito et al. Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research 2006; 12(11 Pt 1):3257- 64 PMID:16740745 |
Note on publication | Describes the generation of monoclonal antibodies against new cell surface targets for treatment of heptacellular carcinomas. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
