Key features and details | |
Cat. No. | MABL-057 |
Name | Anti-Tetanus toxin mAbs |
Clone No. | AFD-G6 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Tetanus |
Basic Information | |
Specificity | G6 recognises the middle domain of the Tetanus toxin. |
Alternative Name | STeNT; pasmogenic toxin; Tentoxylysin |
UniProt | P04958 |
Immunogen | Peripheral lymphocytes from humans hyperimmunized with tetanus toxoid were fused with a mouse/human heteromyeloma. |
Application Notes | G6 has a neutralising activity of 1.4 IU/100 μg IgG (Kamei et al, 1990). From ELISA the Ka of G6 for tetanus toxin was determined as 10 x 10^10 M^1 (Matsuda et al, 1992). |
Antibody First Published | Kamei et al, 1990. Establishment of stable mouse/human-human hybrid cell lines producing large amounts of anti-tetanus human monoclonal antibodies with high neutralizing activity Eur J Epidemiol. 1990 Dec;6(4):386-97. PMID:2091939 |
Note on publication | Describes the original production of the antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |