Key features and details | |
Cat. No. | MABL-071 |
Name | Anti-PSD-95 mAbs |
Clone No. | AFD-K28/43 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, IP, WB, IF |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for PSD-95. It has been shown not to cross-react with DLG1/SAP97, DLG2/Chapsyn-110 or DLG3/SAP102. |
Alternative Name | K28/43R; pSD95; Postsynaptic density protein 95; Disks large homolog 4; Synapse-associated protein 90; DLG4; Dlgh4; SAP-90 |
UniProt | P78352 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein consisting of amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95. |
Application Notes | This antibody has been used in immunoblot analysis of membranes prepared from adult rat and mouse brain (Andrews et al, 2019; PMID:30667360; Rasband et al, 2019). This antibody has also been used in immunofluorescence staining of cultured rat hippocampal neurons and immunohistochemical analysis of adult rat brain sections (Andrews et al, 2019; PMID:30667360).Additionally, this antibody has been used in western blot analysis of rat spinal dorsal horn neurons (Li et al, 2019) and immunogold electron microscopy (Andrews et al, 2019; PMID:30667360). |
Antibody First Published | Rasband et al. Clustering of neuronal potassium channels is independent of their interaction with PSD-95 J Cell Biol. 2002;159(4):663‐672 PMID:12438413 |
Note on publication | Describes the original generation of this antibody and its initial characterisation. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
