Anti-Kv1.1 K+ Channel Extracellular Domain mAbs

Cat. No.

MABL-072

Name

Anti-Kv1.1 K+ Channel Extracellular Domain  mAbs

Clone No.

AFD-K36/15

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IB, IHC

Species Reactivity

Rat, Mouse

Basic Information

Specificity

This antibody is specific for the extracellular domain of the Kv1.1 potassium channel.

Alternative Name

K36/15R; potassium voltage-gated channel subfamily A member 1; IA; RBKI; RCK1; Kcna1; P16388

UniProt

P10499

Immunogen

This antibody was raised by immunising BALB/c mice with a synthetic peptide corresponding to the extracellular domain(amino acids 191-208) of rat Kv1.1

Application Notes

This antibody has been used in   immunoblot analysis of adult mouse and rat crude brain membranes (Andrews et   al, 2019; PMID:30667360). Additionally, this antibody has been used in immunofluorescence staining of hippocampi from adult mice (Andrews et al, 2019; PMID:30667360) and immunohistochemical analysis of mouse auditory brainstem tissue sections (Karcz et al, 2011).

Antibody First Published

Tiffany et al. PSD-95 and SAP97 Exhibit Distinct Mechanisms for Regulating K+ Channel Surface Expression and Clustering J Cell Biol (2000) 148 (1): 147–157. PMID:10629225

Note on publication

Describes the original generation of this antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.