Key features and details | |
Cat. No. | MABL-073 |
Name | Anti-Kv2.1 K+ Channel Ectodomain mAbs |
Clone No. | AFD-K39/25 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, IP, IF |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for the ectodomain of the Kv2.1 potassium channel. |
Alternative Name | K39/25R; potassium voltage-gated channel subfamily B member 1; voltage-gated potassium channel subunit Kv2.1; DRK1; h-DRK1; KCNB1 |
UniProt | Q14721 |
Immunogen | This antibody was raised by immunising BALB/c mice with a synthetic peptide corresponding to the extracellular S1-S2 op (amino acids 211-229) of human Kv2.1 |
Application Notes | This antibody has been used in immunoblot analysis of adult rat brain membranes (Andrews et al, 2019; PMID:30667360), as well as in immunofluorescence analysis of surface Kv2.1 expression by rat hippocampal neurons transfected with Kv2.1 (Lim et al, 2000). This antibody has also been used in immunoprecipitation analysis of mouse brain samples (Pelota et al, 2011). |
Antibody First Published | Lim et al. A Novel Targeting Signal for Proximal Clustering of the Kv2.1 K+ Channel in Hippocampal Neurons Neuron. 2000;25(2): 385‐397. PMID:10719893 |
Note on publication | Describes the original generation of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
