Anti-Neuroligin-3 mAbs

Cat. No.

MABL-090

Name

Anti-Neuroligin-3 mAbs

Clone No.

AFD-N110/29.4

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, IF, IHC

Species Reactivity

Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for the   neuroligin-3 antigen. Cell surface protein involved in cell-cell-   interactions via its interactions with neurexin family members.

Alternative Name

N110/29.4R; Gliotactin homolog;   N110/29; S110-29

UniProt

Q62889

Immunogen

This antibody was raised by   immunising BALB/c mice with the neuroligin-G antigen.

Application Notes

The antibody was used in   immunofluorescense in research on synapses (Davenport et al, 2019;   PMID:30784587). This antibody was used for immunohistochemistry in research   on the retromer which is an endosomal trafficking complex (Binda et al, 2019;   PMID:30602588). Western blotting is a technique usable with this antibody in   research on retromers (Binda et al, 2019; PMID:30602588).

Antibody First Published

Binda et al Sorting nexin 27 rescues   neuroligin 2 from lysosomal degradation to control inhibitory synapse number.   Biochem J. 2019 Jan 25;476(2):293-306. PMID:30602588

Note on publication

 Describes research of the retromer which is an evolutionarily conserved   endosomal trafficking complex that mediates the retrieval of cargo proteins   from a degradative pathway for sorting back to the cell surface.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.