Key features and details | |
Cat. No. | MABL-094 |
Name | Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mAbs |
Clone No. | AFD-N120A/9.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for the neuregulin-HBD antigen in humans, rats and mice. This antigen is a direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. |
Alternative Name | N120A/9.1R; Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-deriv |
UniProt | Q02297 |
Immunogen | This antibody was raised by immunising BALB/c mice with the neuregulin-HBD antigen. |
Application Notes | This antibody has been used for western blotting on proteins from the muscles of rats (Ennequin et al, 2015; PMID:25820551) (Ennequin et al, 2015; PMID:26230680) (Ennequin et al, 2018; PMID:30449185). |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |