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Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mAbs

简要描述:

This antibody is specific for the neuregulin-HBD antigen in humans, rats and mice. This antigen is a direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors.

产品参数:

Cat. No.:MABL-094

Species:Engineer

Species Reactivity:Rat, Human, Mouse

Type:Recombinate

Application:ICC, WB

详细介绍

Key features and details

Cat. No.

MABL-094

Name

Anti-Neuregulin-HBD (Heparin binding domain, Type I/II)  mAbs

Clone No.

AFD-N120A/9.1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ICC, WB

Species Reactivity

Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for the   neuregulin-HBD antigen in humans, rats and mice. This antigen is a direct   ligand for ERBB3 and ERBB4 tyrosine kinase receptors.

Alternative Name

N120A/9.1R; Pro-neuregulin-1,   membrane-bound isoform; Pro-NRG1; Acetylcholine receptor-inducing activity;   ARIA; Breast cancer cell differentiation factor p45; Glial growth factor;   Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-deriv

UniProt

Q02297

Immunogen

This antibody was raised by   immunising BALB/c mice with the neuregulin-HBD antigen.

Application Notes

This antibody has been used for   western blotting on proteins from the muscles of rats (Ennequin et al, 2015;   PMID:25820551) (Ennequin et al, 2015; PMID:26230680) (Ennequin et al, 2018;   PMID:30449185).

Antibody First Published

Andrews et al. A toolbox of IgG   subclass-switched recombinant monoclonal antibodies for enhanced multiplex   immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360

Note on publication

 This article describes the generation of a library of recombinant   monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for   neuroscience research.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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