Anti-Kv3.1b K+ channel mAbs

Cat. No.

MABL-104

Name

Anti-Kv3.1b K+ channel  mAbs

Clone No.

AFD-N16B/8

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ICC, WB, IHC

Species Reactivity

Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for the Kv3.1b K+   channel. The Kv3.1b K+ channel is a voltage-gated potassium channel that   plays an important role in the rapid repolarization of fast-firing brain   neurons.

Alternative Name

N16B/8R; N16B/8; Potassium voltage-gated   channel subfamily C member 1; Kcnc1; NGK2; RAW2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4

UniProt

P25122

Immunogen

This antibody was raised by immunising   BALB/c mice with a fusion protein amino acids 437- 585 (cytoplasmic   C-terminus) of rat Kv3.1b.

Application Notes

Western blot has been preformed on the   brainstem of mice using this antibody (Dagley et al, 2014; PMID:24259518).   This antibody has shown to be useful in the immunostaining of the mouse brain   (Barry et al, 2013; PMID:23487040)

Antibody First Published

Andrews et al. A toolbox of IgG   subclass-switched recombinant monoclonal antibodies for enhanced multiplex   immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360

Note on publication

This article describes the generation of a   library of recombinant monoclonal antibodies (R-mAbs) from a pool of   mAb-producing hybridomas for neuroscience research.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.