Key features and details | |
Cat. No. | MABL-106 |
Name | Anti-INPP4b mAbs |
Clone No. | AFD-N171/17.4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for the INPP4b protein and shows no cross reactivity with INPP4a. INPP4b catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate |
Alternative Name | N171/17.4R; N171/17; Inositol polyphosphate 4-phosphatase type II; INP4B |
UniProt | O15327 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 395- 518 of human INPP4b (also known as Type II inositol-3,4-bisphosphate 4-phosphate. |
Application Notes | This antibody is recommended for the detection and analysis of INPP4b by western blot and immunocytochemistry. For instance, the mouse version of this antibody was used to detect INPP4b by western blot in extracts of COS cells transiently transfected with GFP-tagged INPP4b or untagged Kv2.1 plasmid. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |