Key features and details | |
Cat. No. | MABL-181 |
Name | Anti-IRSp53 mAbs |
Clone No. | AFD-IC65 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, IF, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for IRSp53. IRSp5 is an adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. It is necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. |
Alternative Name | Brain-specific angiogenesis inhibitor 1-associated protein 2; BAIAP2; BAI- associated protein 2; BAI1-associated protein 2; Protein BAP2; Fas ligand-associated factor 3; FLAF3; Insulin receptor substrate p53/p58; IRS-58; IRSp53/58; Insulin receptor substra |
UniProt | Q9UQB8 |
Immunogen | This antibody was raised against the the IRSp53 antigen. |
Application Notes | This antibody is recommended for detection and analysis of IRSp53 by ELISA, immunofluorescence and immunohistochemistry. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | Describes the generation of a library of recombinant monoclonal antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
