Anti-Mitofusin-1 mAbs

Cat. No.

MABL-208

Name

Anti-Mitofusin-1  mAbs

Clone No.

AFD-N111/24R

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB

Species Reactivity

Rat, Mouse

Basic Information

Specificity

This antibody is specific for mitofusin-1. It shows no cross-reactivity against Mitofusin-2.

Alternative Name

Mfn1; Transmembrane GTPase MFN1; N111/24

UniProt

Q811U4

Immunogen

This antibody was raised against a fusion   protein of amino acids 350-580 of mouse Mitofusin- 1.

Application Notes

Immunoblotting was preformed on   whole cardiac extracts from mice with this antibody (Papanicolaou et al,   2012; PMID:22037195).

Antibody First Published

Papanicolaou et al. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death Am J Physiol Heart Circ   Physiol. 2012 Jan 1;302(1):H167-79. PMID:22037195

Note on publication

The generation and initial   characterization of cardiomyocyte-specific Mfn-1 knockout (Mfn-1 KO) mice was   reported.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.