Product Name
Competitive ELISA for detection of PEGylated proteins kit
Principle
Competitive ELISA
Intended Use
This kit is for research use only. Under no circumstances should it be used for therapeutic or diagnostic applications.
Principle Of The Assay
The format of the assay is a direct competitive ELISA.
Background
PEGylation of biologics prolongs their half-life by slowing proteolytic degradation and decreasing the rate of clearance from the circulatory system. The pharmacodynamics of PEGylated proteins are often evaluated using specific assays for the protein itself. That approach often requires the time consuming and expensive construction of an ELISA for the protein of interest. The PEG ELISA manufactured by Mabioway Co., Ltd. allows measurement of the PEG portion of the PEGylated protein and is therefore suitable for assessment of the pharmacodynamics of a range of PEGylated proteins.
Competitive ELISA for detection of PEGylated proteins kit (MAK-0007).pdf