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Anti-CD103 mAbs

简要描述:

This antibody recognizes murine CD103 (Integrin alpha-E). Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall (Uniprot).

产品参数:

Cat. No.:MABL-668

Species:Engineer

Species Reactivity:Mouse

详细介绍

Key features and details

Cat. No.

MABL-668

Name

Anti-CD103 mAbs

Clone No.

AFD- YDBYT 280.2

From

Recombinant Antibody

Isotype

Engineer antibody

Application


Species Reactivity

Mouse

Basic Information

Specificity

This antibody recognizes murine CD103 (Integrin   alpha-E). Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates   adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.   Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked   reduction in the numbers of intraepithelial lymphocytes in the gut and in the   development of gut-associated lymphoid aggregates, supporting a specific role   for this integrin in mediating retention of lymphocytes in the intestinal   wall (Uniprot).

Alternative Name

Integrin alpha-E; Integrin alpha M290

UniProt

Q60677

Immunogen

The original version of this antibody was   raised against murine CD103.

Application Notes

This antibody is recommended for the   detection of murine CD103 ((Integrin alpha-E).

Antibody First Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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