Key features and details | |
Cat. No. | MABL-668 |
Name | Anti-CD103 mAbs |
Clone No. | AFD- YDBYT 280.2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody recognizes murine CD103 (Integrin alpha-E). Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall (Uniprot). |
Alternative Name | Integrin alpha-E; Integrin alpha M290 |
UniProt | Q60677 |
Immunogen | The original version of this antibody was raised against murine CD103. |
Application Notes | This antibody is recommended for the detection of murine CD103 ((Integrin alpha-E). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |