Key features and details | |
Cat. No. | MABL-694 |
Name | Anti-CD11c mAbs |
Clone No. | AFD- OX-42 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC, IHC |
Species Reactivity | Rat |
Basic Information | |
Specificity | This antibody recognizes rat CD11c, the receptor for iC3 strongly expressed on macrophages. |
Alternative Name | iC3b receptor; Integrin alpha X; complement component 3 receptor 4 subunit; ITGAX |
UniProt | |
Immunogen | Resident peritoneal cells from F1 hybrids between PVG-RT1c and PVG-RTu and between PVG- RT1c and DA-RT1a rats. |
Application Notes | The binding of this antibody does not interfere with phagocytosis. |
Antibody First Published | Robinson, White, Mason Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. 1986 Immunology 57:239 PMID:3512425 |
Note on publication | Describes the generation and characterisation of this antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |