Anti-CD138 mAbs

Cat. No.

MABL-710

Name

Anti-CD138 mAbs

Clone No.

AFD- 587CT7.3.6.5.2

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, ELISA, FC, IF

Species Reactivity

Human

Basic Information

Specificity

This antibody is specific for the   extracellular domain of human syndecan-1. Syndecan-1 is a cell membrane   protein that, after its shedding by heparanase enzymes, is accumulated in the   extracellular matrix of some tumours, e.g. myeloma and lung carcinoma, where   it modulates several key processes of tumourigenesis such as cancer cell   proliferation and apoptosis, angiogenesis and metastasis.

Alternative Name

Syndecan-1; SDC1; SYND1; SDC

UniProt

P18827

Immunogen

The original antibody was generated by   immunizing female BALB/c mice with myeloma tumor cells or CD138 protein   antigen.

Application Notes

The screening of hybridomas for specific   antibodies was done using ELISA. Further confirmation of the specificity for   CD138 was done using western blotting. This antibody was also used for   immunofluorescent staining and Flow cytometric analysis of CD138 exoression   on HepG2, T47D and U266 cells (CN104059151).

Antibody First Published

Wang et al. Anti-CD138 monoclonal antibody   variable region sequence and preparation method thereof. CN104059151A

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.