Key features and details | |
Cat. No. | MABL-735 |
Name | Anti-CD16 (FCgRIII) mAbs |
Clone No. | AFD- B88-9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | B88-9 binds to human CD16 at an epitope comprised of LEKDSVTK (aa 21-27), (SWKNTALH (aa 113-120), FHHNS (aa 134-138) and VGSKN (aa 158-162) (Feng et al, 2004). hCD16 is recognized by B88-9 when both bound and unbound to hIgG1 – B88-9-bound CD16 cannot be bound by hIgG1. |
Alternative Name | Low Affinity IgR; Low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; FCGR3A; CD16A; FCG3; FCGR3; IGFR3; Fc-gamma receptor IIIb |
UniProt | Q9ULV2 |
Immunogen | This antibody was raised against FCgRIII expressing cells. |
Application Notes | This antibody binds to CD16, a low affinity Fc receptor on the surface of natural killer cells, neutrophils, monocytes and macrophages. |
Antibody First Published | Tamm A, Schmidt RE. The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding. J Immunol. 1996 Aug 15;157(4):1576-81 PMID:8759741 |
Note on publication | Describes the characterization of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
