Key features and details | |
Cat. No. | MABL-763 |
Name | Anti-CD19 mAbs |
Clone No. | AFD- HD37 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking, IP, SPR, FC, IF, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human CD19, a 95 kDa protein expressed in the B-lymphocyte lineage. |
Alternative Name | Leu12; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19 T-cell surface antigen Leu-12; CD19 |
UniProt | P15391 |
Immunogen | Cells from a hairy cell leukemia patient. |
Application Notes | This antibody binds to CD19 and is able to inhibit B-cell activation (Pezutto 1987). This antibody was measured to have a KD of 4.1 ± 0.3 nM against human CD19 and did not compete with clone FMC63 (available as Ab00613) (Sakemura et al., 2023; PMID: 37879074). |
Antibody First Published | Pezzutto et al. HD37 Monoclonal Antibody: A Useful Reagent for Further Characterization of “Non-T, Non-B” Lymphoid Malignancies Leukocyte Typing II, pp 391-402, 1986, ISBN 978-1-4612-4848-4, DOI 10.1007/978-1-4612-4848-4_33. |
Note on publication | Describes the generation and characterization of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
