Key features and details | |
Cat. No. | MABL-843 |
Name | Anti-CD26 mAbs |
Clone No. | AFD- ZHB-2cF9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibition, WB, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for the extracellular domain of CD26. CD26 is a cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. |
Alternative Name | TP103; ADABP; ADCP-2; Dipeptidyl peptidase 4; EC：3.4.14.5; Adenosine deaminase complexing protein 2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26 |
UniProt | P27487 |
Immunogen | The original antibody was obtained from a human single-chain antibody phage display library by solid-phase affinity screening of CD26 extracellular region protein. |
Application Notes | The specificity of the antibody was confirmed by ELISA analysis. The original format of the antibody could specifically bind to the CD26 extracellular domain protein. The antibody could detect CD26 expressed on the surface of human mesothelioma cells NCI-H2452 by immunofluorescence analysis. The antibody was able to inhibit the binding of human mesothelioma cell NCI-H2452 expressing CD26 to ECM. Further, the antibody could inhibit the proliferation of mesothelioma cells and colon cancer cells with high expression of CD26 (WO2015089881A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
