Key features and details | |
Cat. No. | MABL-847 |
Name | Anti-CD27 mAbs |
Clone No. | AFD- LG8A6 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for human and mouse CD27. CD27 is a receptor for CD70/CD27L. It may play a role in survival of activated T-cells. CD27 might also play a role in apoptosis through association with SIVA1. |
Alternative Name | LG.8A6; CD27 antigen; CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7 |
UniProt | P41272 |
Immunogen | The hamster version of this antibody was raised by immunizing a armenian hamster with armenian hamster fibroblasts transfected with the mouse CD27 DNA. |
Application Notes | To study expression of CD27 on T lymphocytes, immunoprecipitation was performed on C57BL/6 thymocytes using the hamster version of this antibody (Gravestein et al, 1995; pmid：7547681). |
Antibody First Published | Gravestein et al. Novel mAbs reveal potent co-stimulatory activity of murine CD27 Int Immunol. 1995 Apr;7(4)：551-7. PMID：7547681 |
Note on publication | The generation of mAbs to murine CD27, by an efficient method involving the use of transfected Armenian hamster fibroblasts. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
