Key features and details | |
Cat. No. | MABL-854 |
Name | Anti-CD28 mAbs |
Clone No. | AFD- CBL 562 (204.12) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vitro, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for CD28. |
Alternative Name | TP44; T-cell-specific surface glycoprotein CD28; 204.12 |
UniProt | P10747 |
Immunogen | The original antibody was raised by immunizing a mouse with CD28. |
Application Notes | The original version of this antibody was used to activate purified human peripheral blood leucocytes (Sandilands et al., 2010; PMID:20964641). The original version of this antibody was also used for immunofluorescence staining on frozen biopsy sections from vastus lateralis or tibialis anterior muscle (Fasth et al., 2009; PMID:19752224). |
Antibody First Published | Fasth et al. T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells J Immunol. 2009 Oct 1;183(7):4792-9. PMID:19752224 |
Note on publication | The original paper aims to characterize T cells in muscle tissue and circulation and to investigate their association to clinical phenotype. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
