Key features and details | |
Cat. No. | MABL-869 |
Name | Anti-CD3 epsilon mAbs |
Clone No. | AFD- 500A2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Activate, FC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | The 25-kDa ε chain of the T-cell receptor-associated CD3 complex expressed on thymocytes, mature T lymphocytes, and NK-T cells on many mouse stains. |
Alternative Name | CD3e; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain |
UniProt | P22646 |
Immunogen | T cell receptor complexes derived from mouse C6VL-BS thymoma cells (C57BL/Ka) . |
Application Notes | This antibody binds to murine CD3 epsilon. It partially cross-blocks binding of clone 145-2C11 (Ab00112) indicating that overlapping epitopes are detected by these antibodies. |
Antibody First Published | Allison, J. P. The T Cell Receptor UCLA Symposia on Molecular and Cellular Biology, New Series (eds Kappler, J. & Davies, M.) (Lissabon, New York, 1987) PMID:n/a |
Note on publication | Describes the making of the hamster monoclonal antibodies directed against the epsilon chain of murine CD3. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
