Anti-CD3 epsilon mAbs

Cat. No.

MABL-870

Name

Anti-CD3 epsilon mAbs

Clone No.

AFD- UCHT1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

 FC, IHC

Species Reactivity

Human

Basic Information

Specificity

 Epitopes on CD3-ε found in heterodimers with   CD3-δ and with CD3-γ of α/β T cell receptor (TCR).

Alternative Name

 CD3e; T-cell surface glycoprotein CD3 epsilon   chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3-ε;

UniProt

 P07766

Immunogen

 Human infant thymocytes.

Application Notes

This antibody binds to murine CD3 epsilon.   It partially cross-blocks binding of clone 500A2 (Ab00212) indicating that   overlapping epitopes are detected by these antibodies.

Antibody First Published

Beverley PC, Callard RE. Distinctive   functional characteristics of human "T" lymphocytes defined by E   rosetting or a monoclonal anti-T cell antibody. Eur J Immunol. 1981   Apr;11(4):-329:34. PMID:6788570

Note on publication

Describes the generation of the antibody,   shows it recognised human T lymphocytes using flow cytometry and functional  assays.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.