Cat. No.
MABL-1350
Application
LFA, ELISA
Isotype
Engineer antibody
Species Reactivity
Indian Common Krait (Bungarus caeruleus), Naja naja (Indian cobra)
Clone No.
MAb1.1
From
Recombinant Antibody
Specificity
This antibody binds the cytotoxin 7 protein found in the venom of Naja naja (Indian cobra). This antibody shows specific binding for the peptide II (CYKMYMVSNKTVPVKRGCID) of the cytotoxin-7. This antibody also reacts with krait venom (Bungarus caeruleus). Cytotoxin 7 shows cytolytic activity on many different cells by forming pore in lipid membranes. In vivo, it increases heart rate or kills the animal by cardiac arrest. It also has hemolytic activity towards human erythrocytes (EC50=0.171 uM).
Alternative Names
CTX7; CTX-7
UniProt
P86382
Immunogen
The original antibody was generated by immunizing mice with recombinant cytotoxin-7 (rCTX-7) protein from Naja naja (Indian cobra).
Application Notes
The binding reactivity of this antibody towards peptide II, rCTX-7, cobra venom and krait venom was evaluated using ELISA.This antibody was also used in the generation of a lateral flow assay for the differential detection of cobra (Naja naja) and krait (Bungarus caeruleus) venom from vipers (Daboia russelii and Echis carinatus). (IN202041050355).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
