Key features and details | |
Cat. No. | MABL-880 |
Name | Anti-CD32 mAbs |
Clone No. | AFD- AT10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | Binds specifically to human CD32. |
Alternative Name | FcgRIIb; Low affinity immunoglobulin gamma Fc region receptor II-b; FCGR2B |
UniProt | P31994 |
Immunogen | Human CD32. |
Application Notes | The antibody binds to CD32, a surface receptor protein with a low affinity for IgG antibodies. |
Antibody First Published | Greenman et al. Characterization of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab’)2 derivative for recruitment of cytotoxic effectors. Molecular Immunology PMID:1835758 |
Note on publication | Describes the production and characterisation of a mouse monoclonal antibody against CD32 as well as the construction of a F(ab’2) antibody of T10 for further binding studies. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |