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Anti-CD35 (complement receptor 1) mAbs

简要描述:

Recognises an epitope on CD35 (CR1, 190 kDa), but not on CD21 (CR2, 145-150 kDa), which are alternative splice variants of primary Cr2 gene transcripts.

产品参数:

Cat. No.:MABL-895

Species:Engineer

Species Reactivity:Mouse

Type:Recombinate

Application:IP, WB, FC, IHC-Fr

详细介绍

Key features and details


Cat. No.

MABL-895

Name

Anti-CD35 (complement receptor 1)   mAbs

Clone No.

AFD- 8C12

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, WB, FC, IHC-Fr

Species Reactivity

Mouse

Basic Information


Specificity

Recognises an epitope on CD35 (CR1, 190   kDa), but not on CD21 (CR2, 145-150 kDa), which are alternative splice   variants of primary Cr2 gene transcripts.

Alternative Name

 CR1 ; C3BR; C4BR; CD35; KN

UniProt

 P17927

Immunogen

 Purified murine CR1 protein.

Application Notes

This antibody recognises murine CD35, expressed   on the majority of peripheral B-cells and peritoneal macrophages and upon   fMet-Leu-Phe stimulation also on

Antibody First Published

Kinoshita et al. Monoclonal antibodies to   mouse complement receptor type 1 (CR1). Their use in a distribution study   showing that mouse erythrocytes and platelets are CR1-negative. J Immunol.   1988 May 1;140(9):3066-72 PMID:2966205

Note on publication

Describes the generation and   characterization of this antibody.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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