Cat. No.
MABL-1543
Application
IP, WB, Block, ELISA
Isotype
Engineer antibody
Species Reactivity
Primate, Human, Mouse
Clone No.
OX23
From
Recombinant Antibody
Specificity
This antibody binds to factor H, a cofactor in the inactication the complement cascade.
Alternative Names
CHF; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS; OX-23
UniProt
P08603
Immunogen
Native protein purified from plasma.
Application Notes
This antibody binds to Factor H and has been used to determine Factor H levels in a sandwich ELISA assay (Daniels-Treffandier, 2016). Alone it has no effect on Factor H activity, but it is able to reduce the increase in cofactor activity mediated by the antibody clone OX24.
Antibody First Published
Sim et al. Monoclonal antibodies against the complement control protein factor H (beta 1 H). Biosci Rep. 1983 Dec;3(12):1119-31. PMID:6199050
Note on publication
Describes the generation and functional characterisation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
