Anti-CD37 mAbs

Cat. No.

MABL-900

Name

Anti-CD37 mAbs

Clone No.

AFD- G28-1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

depleting

Species Reactivity

Human

Basic Information

Specificity

This antibody recognises CD37, which is a cell   surface protein, present mostly on mature B cells and B cell malignancies.

Alternative Name

TSPAN-26; Leukocyte antigen CD37;   Tetraspanin-26; tetraspanin; Tspan- 26

UniProt

P11049

Immunogen

This antibody was raised by immunizing mice   with CD37.

Application Notes

G28-1 antibody was used to deplete normal   and malignant B cells (Hayden-Ledbetter, unpublishesd). This antibody and   antibody fragments derived therefrom have been used in the research and   trials on the generation of novel immunotherapuetic agents, alternative to   anti-CD20 therpaies (rituximab) (Robak and Robak, 2014).

Antibody First Published

Ledbetter et al. Monoclonal antibodies to a   new gp40-45 (CD37) B cell associated cluster group modulate B cell   proliferation. LEUCOCYTE TYPING III: WHITE CELL DIFFERENTIATION ANTIGENS:   339-341; Oxford University Press, USA (1987)

Note on publication

This article decribes the generation of the   G28-1 antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.