Cat. No.
MABL-1613
Application
BLI, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
SH7
From
Recombinant Antibody
Specificity
The antibody is specific for FLNB. FLNB is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskeletal network, to control and guide proper skeletal development.
Alternative Names
Fh1; FLN-B; filamin B; Filamin-B; ABP-278; ABP-280 homolog; Actin- binding-like protein; Beta-filamin; Filamin homolog 1; Filamin-3; Thyroid autoantigen; Truncated actin- binding protein; Truncated ABP
UniProt
O75369
Immunogen
The original antibody was generated by immunizing mice with FLNB antigen.
Application Notes
The specificity of the original format of the antibody was confirmed by ELISA analysis. The binding kinetics of the antibody to the full length FLNA protein was measured by BLI (Kd= 1 nM) (WO2018085441A1).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
