Cat. No.
MABL-1848
Application
WB, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
F3.3
From
Recombinant Antibody
Specificity
Recognising anti-class II HLA molecules.
Alternative Names
HLA-DR; HLA class II related epitope
UniProt
Immunogen
Application Notes
This antibody has been show to work by flow-cytometry and western blot. Dechant et al (PMID: 12393717) used a human IgA2-chimeric version of this antibody to study IgA-mediated cell killing.
Antibody First Published
Elsässer D, Valerius T, Repp R, Weiner GJ, Deo Y, Kalden JR, van de Winkel JG, Stevenson GT, Glennie MJ, Gramatzki M. HLA class II as potential target antigen on malignant B cells for therapy with bispecific antibodies in combination with granulocyte colony-stimulating factor. Blood. 1996 May 1;87(9):3803-12. PMID:8611706
Note on publication
Describes the preparation and characterisation of anti human HLA class II antibody by of ADCC of G-CSF primed PMN expressing in the presence of F3.3 to HLA class II related epitope (HLA- DR).
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
