Cat. No.
MABL-1887
Application
ELISA, FC, IF
Isotype
Engineer antibody
Species Reactivity
Human, Mouse
Clone No.
6H8
From
Recombinant Antibody
Specificity
This antibody is specific for HSP90 alpha. It binds to the epitope between amino acid 712 and 723.
Alternative Names
HSP 86; HSP86; LAP-2; LPS-associated protein 2; Heat shock 86 kDa; Renal carcinoma antigen NY-REN-38; Heat shock protein family C member 1; Renal carcinoma antigen NY- REN-38; Heat shock protein HSP 90-alpha
UniProt
P07900
Immunogen
This antibody was raised by immunizing a BALB/c mice with human recombinant HSP90 alpha.
Application Notes
The original antibody was used for an ELISA on different epitopes of human HSP90 alpha. It showed that the epitope of this antibody is HSP90 alpha amino acids 712-723. This antibody was used for flow cytometry on DC2.4 cells. The antibody was used for immunostaining on DC2.4 cells, here it showed that the antibody was quickly internalized after binding to HSP90. This ability to internalize the antibody can also be leveraged to internalize compounds coupled to the antibody. This antibody was used in vitro, here it showed it could induce cytokine production in dendritic cells (US20110280881A1).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
