Cat. No.
MABL-2296
Application
FC, IF, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
LZ-2
From
Recombinant Antibody
Specificity
This antibody recognizes intracellular human lysozyme/muramidase expressed by virtually all myelomonocytic cells, macrophages and their precursors.
Alternative Names
1,4-beta-N-acetylmuramidase C
UniProt
P61626
Immunogen
The original mouse IgG1 version of this antibody was raised by immunizing mice against human lysozyme.
Application Notes
The original mouse IgG1 clone is primarily used in analytics. On group used this antibody to sketch an immunophenotype for several leukemia patients (Perea et al., 2005; PMID: 16095690). Another group used the antibodies with immunofluorescence to inspect lysozymes withing patiens with specific granule deficiency, a rare disease (Serwas et al., 2018; PMID: 29651288). A final group used LZ-2 in combination with flow cytometry to analyze the development of bone marrow with and without myeloperoxidase (Scholz et al., 2004; PMID: 15003312)
Antibody First Published
Lanza et al. Comparative Analysis of Different PermeabilizationMethods for the Flow Cytometry Measurementof Cytoplasmic Myeloperoxidase and Lysozymein Normal and Leukemic Cells Cytometry. 1997 Jun 15;30(3):134-44 PMID:9222099
Note on publication
Describes the usuage of an antibody in the same group as LZ-2
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
