Cat. No.
MABL-2319
Application
WB, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
1032
From
Recombinant Antibody
Specificity
This antibody is specific for the human major vault protein.
Alternative Names
MVP; Lung resistance-related protein
UniProt
Q14764
Immunogen
The original antibody was generated by immunizing a BALB/c mouse with major vault protein.
Application Notes
The original version of this antibody was used for an immunohistochemistry experiment on human FFPE tissue blocks (Ramberg et al., 2021; PMID:33609362), on MCF-7 breast cancer cells (Abbondanza et al., 1998; PMID:9628887). Further this antibody was used for immunohistochemistry on cervix carcinoma tissues (Lloret et al., 2009; PMID:19251084), on human lung tissue (Schroeijers et al., 2001; PMID:11668191). Finally, a western blot on human liver tumour and nontumor tissue lysates was performed using this antibody (Megger et al., 2013; PMID:23462207).
Antibody First Published
Abbondanza et al. Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell J Cell Biol. 1998 Jun 15;141(6):1301-10. PMID:9628887
Note on publication
The original paper studies the estrogen receptor and identified the major vault protein using this antibody
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
