Key features and details | |
Cat. No. | MABL-983 |
Name | Anti-CD45 mAbs |
Clone No. | AFD- YTS165.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Functional Studies, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody recognises mouse CD45. which is a leukocyte marker. |
Alternative Name | PTPRC; YBM42; YBM/42; YBM42.2.2; Receptor-type tyrosine-protein phosphatase C; L-CA; CD45; Lymphocyte antigen 5; Leukocyte common antigen; T200 |
UniProt | P06800 |
Immunogen | This antibody was raised by immunising rats with mouse tissue containing CD45 positive cells. |
Application Notes | YTS165.1 antibody might be used to identify various leukocytes. It was used in immunohistochemistry stainings to label mouse spine microglia (Hoek et al.,2000). Hoek and colleagues (2000) incubated WEHI-231P cells with this antibody to investigate the effects of CD45 targeting on bcl-2 expression Finally, it has also been shown to be synergistic with YW 62.3. |
Antibody First Published | Choi et al. The role of bcl-XL in CD40-mediated rescue from anti-mu- induced apoptosis in WEHI-231 B lymphoma cells. Eur J Immunol. 1995 May;25(5):1352-7. PMID:7539757 |
Note on publication | This article describes an early application of the YTS165.1 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
