Cat. No.
MABL-2395
Application
WB, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
12F3A4C11
From
Recombinant Antibody
Specificity
The antibody is specific for MPO. Myeloperoxidase (MP0) is a cationic glycoprotein with a relative molecular weight of 133-155kD and an isoelectric point of 1.0 secreted by neutrophils, macrophages and monocytes. MPO is part of the host defense system of polymorphonuclear leukocytes and it is responsible for microbicidal activity against a wide range of organisms.
Alternative Names
CGMCC No. 19684; myeloperoxidase
UniProt
P05164
Immunogen
The original antibody was generated by immunizing mice with MPO.
Application Notes
The antibody specifically detected MPO by Western blot analysis. The antibody 12F3A4C11 and a commercial rabbit polyclonal antibody were used to stain granulocytic sarcoma. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 12F3A4C11 was higher than the commercial antibody. The antibody and the commercially available antibody were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN112194724B).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
