Cat. No.
MABL-2532
Application
in vitro, WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Lake Victoria marburgvirus
Clone No.
MARV-C
From
Recombinant Antibody
Specificity
This antibody is specific for the Marburgvirus Nucleoprotein.
Alternative Names
NP; Protein N; Nucleoprotein; Nucleocapsid protein; sdAb C
UniProt
P27588
Immunogen
The original antibody was raised by immunizing a llama with the Marburgvirus Nucleoprotein.
Application Notes
The original version of this antibody was used for an ELISA on nucleoprotein from polio (Garza et al., 2017; PMID:29038656) (Darling et al., 2017; PMID:29021793). The monomeric and dimeric version of this antibody were used for a western blot on HEK 293T cells (Garza et al., 2017; PMID:29038656). Furthermore the ability of this antibody to crosslink nucleoprotein (NP) in vitro was tested (Darling et al., 2017; PMID:29021793).
Antibody First Published
Darling et al. Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging Front Immunol. 2017; 8: 1197. PMID:29021793
Note on publication
The original paper studied whether RNC would be ideal targets for crosslinkers engineered to promote aberrant protein–protein interactions.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
