Cat. No.
MABL-2604
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
1B5
From
Recombinant Antibody
Specificity
This antibody binds human PAR2 or proteinase-activated receptor 2 upstream to its cleavage site. PAR2 acts as a receptor for trypsin and trypsin-like enzymes coupled to G proteins.
Alternative Names
F2RL1; PAR-2; GPR11; Proteinase-activated receptor 2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1
UniProt
P55085
Immunogen
The original antibody was generated by immunizing XenoMouse™ with PAR-2 antigen.
Application Notes
The initial screening of this antibody for reactivity for PAR2 was done using ELISA. The equilibrium dissociation constant (KD) of this antibody was obtained using KinExA® software and by “n- curve analysis” and it was reported that the original antibody had a KD of 3.39 nM with a 95% confidence interval of 1.36 to 5.47 nM (US8357367).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
