Cat. No.
MABL-2867
Application
SPR
Isotype
Engineer antibody
Species Reactivity
Specie independent
Clone No.
5F7
From
Recombinant Antibody
Specificity
The antibody is specific for STX. It cross reacts with dc-STX. STX is a potent neurotoxin and the best-known paralytic shellfish toxin. Ingestion of saxitoxin by humans, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the illness known as paralytic shellfish poisoning.
Alternative Names
STX; [(3aS,4R,10aS)-10,10-dihydroxy-2,6-diiminooctahydro-1H,8H- pyrrolo[1,2-c]purin-4-yl]methyl carbamate
UniProt
Immunogen
The original antibody was generated by immunizing mice with STX-glucose oxidase immunogen.
Application Notes
The binding affinity of the original format of the antibody to STX was measured by surface plasmon resonance (Kd= 2.6 nM). Further, the antibody was used for developing an anti-STX xMAP assay (Shriver-Lake et al., 2017; PMID: 27879646).
Antibody First Published
Immunochemical Approaches to the Analysis of Paralytic Shellfish Poisoning Toxins
Note on publication
The paper describes the generation and characterization of the antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
