Key features and details | |
Cat. No. | MABL-1045 |
Name | Anti-CD56 mAbs |
Clone No. | AFD- RNL-1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IF, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for CD56. |
Alternative Name | N-CAM; N-CAM-1; NCAM-1; Neuronal Cell Adhesion Molecule; Neural cell adhesion molecule 1 |
UniProt | P13591 |
Immunogen | The original antibody was generated by using a NCI-H82 cell preparation as an immunogen. |
Application Notes | The original antibody stained CD56 in NCI-H82 cells (Broers et al., 1991; PMID: 1845952). The antibody was reactive with SCLC, lung carcinoids, renal cancers, and some sarcomas. The antibody was reactive in normal neuronal tissues, and endocrine glands, such as pancreatic islet cells, pituitary gland, and adrenal medulla. The antibody reacted positively in the immunofluorescence assay with the NCAM-transfected 3T3 cells (Boerman et al., 1991; PMID: 1645701). The antibody was used to detect CD56 on SCLC cell lines by immunohistochemistry (Borghtet al., 2018; PMID: 30050775). |
Antibody First Published | Broers et al. Novel antigens characteristic of neuroendocrine malignancies Cancer. 1991 Feb 1;67(3):619-33. PMID:1845952 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
