Cat. No.
MABL-3043
Application
WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Clostridium tetani
Clone No.
5E 4
From
Recombinant Antibody
Specificity
This antibody recognizes tetanus toxoid and binds to the epitope VH Q52N; VK 12/13 (recognizes linear epitopes).
Alternative Names
Tetanus toxin heavy chain; Tetanus toxin chain H; tetanus toxin; Tentoxylysin; 3.4.24.68
UniProt
P04958
Immunogen
The original version of this antibody was raised against tetanus toxoid.
Application Notes
Tetanus also known as lockjaw is caused by an infection with the bacterium Clostridium tetani, which is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin such as a cut or puncture wound by a contaminated object. They produce toxins that interfere with normal muscle contractions. This antibody can be used to bind and detect tetanus toxoid in Western blot and ELISA.
Antibody First Published
Kenimer et al. Monoclonal antibodies as probes of tetanus toxin structure and function Infect Immun. 1983 Dec;42(3):942-8. doi: 10.1128/iai.42.3.942-948.1983. PMID:6642671
Note on publication
Describes anti-tetanus antibodies.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
