Cat. No.
MABL-3084
Application
WB, ELISA, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
7H2
From
Recombinant Antibody
Specificity
The original antibody is specific for TIM-3. TIM-3 is a type I transmembrane protein and contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion.
Alternative Names
CD366; Hepatitis A virus cellular receptor 2; Hepatitis A virus cellular receptor 2; HAVcr-2; T-cell immunoglobulin and mucin domain-containing protein 3; TIMD-3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; D5D5R; E3; CGMCCNO 20763
UniProt
Q8TDQ0
Immunogen
The original antibody was generated by immunizing mice with recombinant TIM-3 protein.
Application Notes
The antibody specifically detected TIM-3 protein in Western blot analysis. The antibody 7H2 and the commercial antibody D5D5R were used to stain tonsils and appendix tissue. Results showed the antibody specificity is comparable to the commercial antibody (CN113234158A).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
