Cat. No.
MABL-3170
Application
WB, FC, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
6E 6
From
Recombinant Antibody
Specificity
This antibody recognizes human ULBP4 which binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Alternative Names
NKG2DL4; Retinoic acid early transcript 1E; Lymphocyte effector toxicity activation ligand; NKG2D ligand 4; N2DL-4; RAE-1-like transcript 4; UL16-binding protein 4; ULBP-4
UniProt
Q8TD07
Immunogen
This antibodhy was raised against purified human ULBP.
Application Notes
This antibody is recommended for the detection and analysis of human ULBP4. It has been successfully used in the identification of ULBP4 in flow cytometry, western blot and immunofluorescence. The antibody could detect ULBP4 surface expression on EBV-infected cells and on placental exosomes by flow cytometry (Zöller et al., 2018; PMID: 29651291 and Hedlund et al., 2009; PMID: 19542445).
Antibody First Published
Vankayalapati et al. Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium J Immunol. 2005 Oct 1;175(7):4611-7. doi: 10.4049/jimmunol.175.7.4611. PMID:16177106
Note on publication
This paper describes the use of the anti-ULBP4 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
