Key features and details | |
Cat. No. | MABL-1121 |
Name | Anti-CD8 mAbs |
Clone No. | AFD- RIV11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognizes human CD8 which is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). CD8 is a T-cell co-receptor involved in the recognition of MHC class I molecules. It is present on cytotoxic/suppressor T lymphocytes. |
Alternative Name | CD8; CD8A; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; Leu2; p32 |
UniProt | P01732 |
Immunogen | This antibody was raised by immunizing mice with human peripheral lymphocytes. |
Application Notes | The antibody RIV11 is recommended for the detection and analysis of CD8 via flow cytometry and immunofluorescence staining of cells and tissues. |
Antibody First Published | Banchereau et al. Anti-cd8 antibodies block priming of cytotoxic effectors and lead to generation of regulatory cd8+ t cells. US20090304659A1 |
Note on publication | This patent describes the antibody RIV11. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
