Key features and details | |
Cat. No. | MABL-1123 |
Name | Anti-CD8 mAbs |
Clone No. | AFD- YTC 182.20 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Monkey, Human, Rhesus Monkey, Cynomolgus Monkey |
Basic Information | |
Specificity | This antibody recognises human CD8. CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). CD8 is a T-cell co-receptor involved in the recognition of MHC class I molecules. It is present on cytotoxic/suppressor T lymphocytes. |
Alternative Name | Leu2; CD8; CD8A; T-cell surface glycoprotein CD8 alpha chain; T- lymphocyte differentiation antigen T8/Leu-2; CD8a; p32; YTC182.20 |
UniProt | P01732 |
Immunogen | Rats were immunised with mouse L cells transfected with human CD8 gene. Subsequently, spleen cells from the immunised DA rat were fused with cells of the rat Y3/Ag.1.2.3 myeloma line. |
Application Notes | YTC 182.20 antibody is recommended for flow cytometric analysis of CD8 positive cells. It is synergistic with Ab01038. |
Antibody First Published | Jonekr et al. Reactivity of mAb specific for human CD markers with Rhesus monkey leucocytes. Leucocyte Typing IV. Oxford University Press p 1058-1063 |
Note on publication | The article provides background information for the YTC 182.20 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
