Key features and details | |
Cat. No. | MABL-1124 |
Name | Anti-CD8 alpha mAbs |
Clone No. | AFD- YTS 105.18 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Block, FC, IF, IHC-Fr |
Species Reactivity | Mouse |
Basic Information | |
Specificity | Recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo. |
Alternative Name | Lyt-2; CD8A Antibody; CD8a molecule Antibody; CD8a antigen Antibody; OKT8 T-cell antigen Antibody; Leu2 T-lymphocyte antigen Antibody; T8 T-cell antigen Antibody; T cell co- receptor Antibody; p32 Antibody; CD8 Antibody; Leu2 Antibody; T-cell antigen Leu2 |
UniProt | P01731 |
Immunogen | Ly-2-transfected mouse L cells. |
Application Notes | This antibody can be used to stain for murine CD8 and can be used to block interaction with CD8. |
Antibody First Published | Qin SX, Wise M, Cobbold SP, Leong L, Kong YC, Parnes JR, Waldmann H. Induction of tolerance in peripheral T cells with monoclonal antibodies. Eur J Immunol. 1990 Dec;20(12):2737-45. PMID:1702726 |
Note on publication | Describes the generation of this antibodies and its characterization, including its funtion in suppressing skin graft rejection. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
